Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytosine and FoL fragment 717, imidazo[2,1-b][1,3]thiazol-6-ylmethanol
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Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytosine and FoL fragment 717, imidazo[2,1-b][1,3]thiazol-6-ylmethanol Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 6-AMINOPYRIMIDIN-2(1H)-ONE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-03-25 Release date: 2010-04-07 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011
假鼻疽伯克霍尔德菌（Burkholderia pseudomallei）来源的2-C-甲基-D-赤藓糖醇2,4-环二磷酸合酶（2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase）与胞嘧啶（cytosine）、FoL片段717及咪唑并[2,1-b][1,3]噻唑-6-基甲醇的晶体结构
描述符：2-氨基-2-羟甲基丙烷-1,3-二醇、2-C-甲基-D-赤藓糖醇2,4-环二磷酸合酶、6-氨基嘧啶-2(1H)-酮……
作者：西雅图传染性疾病结构基因组学中心（Seattle Structural Genomics Center for Infectious Disease, SSGCID）
存档日期：2010-03-25
发布日期：2010-04-07
最后修改日期：2023-09-06
检测方法：X射线衍射（分辨率1.8 Å）
引用文献：《利用片段筛选辅助传染性疾病药物靶点结构解析：假鼻疽伯克霍尔德菌MECP合酶》，《结构与功能基因组学杂志》（J Struct Funct Genomics），第12卷，2011年
创建时间：
2010-03-25
