Human ARTD3 (PARP3) - Catalytic domain in complex with inhibitor ME0355
收藏Protein Data Bank Japan2023-11-08 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/4gv0
下载链接
链接失效反馈官方服务：
资源简介：
Human ARTD3 (PARP3) - Catalytic domain in complex with inhibitor ME0355 Descriptor: 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1S)-1-(pyridin-2-yl)ethyl]propanamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 3 Authors: Karlberg, T, Thorsell, A.G, Lindgren, A.E.G, Ekblad, T, Spjut, S, Andersson, C.D, Weigelt, J, Linusson, A, Elofsson, M, Schuler, H. Deposit date: 2012-08-30 Release date: 2013-06-19 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ARTD3/PARP3 Acs Chem.Biol., 8, 2013
人类ARTD3（PARP3）—— 与抑制剂ME0355复合的催化结构域。描述信息：3-(4-氧代-3,4-二氢喹唑啉-2-基)-N-[(1S)-1-(吡啶-2-基)乙基]丙酰胺、二甲基亚砜（Dimethyl Sulfoxide）、聚[ADP-核糖]聚合酶3。作者：Karlberg, T、Thorsell, A.G、Lindgren, A.E.G、Ekblad, T、Spjut, S、Andersson, C.D、Weigelt, J、Linusson, A、Elofsson, M、Schuler, H。提交日期：2012-08-30；发布日期：2013-06-19；最后修改日期：2023-11-08。实验方法：X射线衍射（分辨率1.9 Å）。引用文献：对ADP-核糖基转移酶ARTD3/PARP3具有选择性的PARP抑制剂，《ACS Chem.Biol., 8, 2013》。
创建时间：
2012-08-30
