RNA-sequencing data from: The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML

This dataset includes RNA sequencing (RNA-seq) data from 120 samples representing 112 adults with acute myeloid leukemia (AML), diagnosed at Lund University Hospital, Sweden, between 2014 and 2018. The median age of patients was 64 years (range 18-86). RNA was extracted from bone marrow (n=102) or peripheral blood (n=18) taken at diagnosis (n=105), relapse (n=14), or during disease (n=1). Libraries were constructed using Illumina Truseq RNA library prep kit v2 and sequenced on Illumina NextSeq 500.

本数据集包含来自瑞典隆德大学医院2014年至2018年间诊断的112名急性髓系白血病（AML）成年患者（年龄中位数为64岁，范围18-86岁）的RNA测序（RNA-seq）数据。其中，102例患者的RNA来源于骨髓，18例患者的RNA来源于外周血，样本采集时间分别为诊断时（n=105）、复发时（n=14）或疾病过程中（n=1）。数据文库的构建采用Illumina Truseq RNA文库制备试剂盒v2，并在Illumina NextSeq 500测序仪上进行测序。