Characteristics of APOA1 S36A, F71Y, K107del, and L144R heterozygotes and noncarriers in the Copenhagen City Heart Study (n = 10,330) and the Copenhagen General Population study (n = 45,239).

Values are median (interquartile range) or percentage. Mann-Whitney U-test or Fishers exact test was used for continuous and categorical traits, respectively. Lipid-lowering therapy was self-reported. Physical inactivity, drinking, smoking, hypertension and diabetes were dichotomized and defined as physical inactivity (less than 2–4 hours per week of light physical activity at leisure time), drinking (more than 1 drink per week), current smoking, hypertension (systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg, and/or use of antihypertensive therapy), and diabetes (self-reported disease, current use of anti-diabetic medication, and/or nonfasting plasma glucose >11.0 mmol/L). LDL cholesterol levels were calculated using the Friedewald equation if triglycerides were ≤4 mmol/L, but measured directly at higher triglyceride levels.aPbP