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Wild - type and PU.1 Q202L mutant mice ST - HSC (lin- c-kit+ Sca-1+ CD150- CD48-) and GMP (lin- c-kit+ Sca-1- CD16/32hi CD34+)

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27873
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Identification of differentially regulated genes in the PU.1 Q202L point mutant that disrupts association with c-Jun. The goal was to identify PU.1 target genes that depend on the co-activation of PU.1 by c-Jun. Mice have normal ST-HSC but lack normal GMP, so a population of GMP-like cells was used in the mutant. Sorted cell populations from homozygous PU.1 Q202L
创建时间:
2022-09-27
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