Crystal structure of human PHGDH complexed with Compound 15
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of human PHGDH complexed with Compound 15 Descriptor: (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid, D-3-phosphoglycerate dehydrogenase, D-MALATE Authors: Olland, A, Lakshminarasimhan, D, White, A, Suto, R.K. Deposit date: 2019-06-30 Release date: 2019-07-24 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.93 Å) Cite: Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells. Bioorg.Med.Chem.Lett., 29, 2019
创建时间：
2019-06-30
