首页/数据集/Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress. Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress

Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress. Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress

NIAID Data Ecosystem2026-03-11 收录

SLFN11功能研究

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数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA591584 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2019-11-25

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核苷酸切除修复

Replication stress (RS) fuels genomic instability and cancer development and may contribute to aging, raising the need to identify factors involved in cellular responses to such stress. Here, we prese

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Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress [ATAC-seq_K562]. Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress [ATAC-seq_K562]

染色质可及性调控

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Schlafen 11 (SLFN11) has recently arisen as a novel cellular restriction factor against replication stress. Here we show that SLFN11 increases chromatin accessibility genome-wide, dominantly at promot

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Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress [RNA-seq_CHK1i]. Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress [RNA-seq_CHK1i]

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染色质重塑

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NR4A1 suppresses cancer replication stress through R-loop-dependent inhibition of immediate early gene transcriptional elongation [ATAC-seq]. NR4A1 suppresses cancer replication stress through R-loop-dependent inhibition of immediate early gene transcriptional elongation [ATAC-seq]

癌症转录调控

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Deregulation of oncogenic proliferative signals triggers replication stress in cancer cells to which they must adapt. Immediate early genes (IEGs), identified by their rapid stress-induced transient b

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Genome-wide binding of hSTN1 in response to hydroxyurea-induced replication stress

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ChIP-seq基因靶点分析

We find that hSTN1 is preferentially enriched at GC-rich repetitive sequences genome-wide after hydroxyurea treatment. HeLa cells stably expressing myc-tagged hSTN1 were treated with 2 mM hydroxyurea,

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Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress. Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress

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