Crystal Structure of Pim-1 Kinase in complex with inhibitor (2E,5Z)-2-(2-chlorophenylimino)-5-(4-hydroxy-3-nitrobenzylidene)thiazolidin-4-one
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Crystal Structure of Pim-1 Kinase in complex with inhibitor (2E,5Z)-2-(2-chlorophenylimino)-5-(4-hydroxy-3-nitrobenzylidene)thiazolidin-4-one Descriptor: (2Z,5Z)-2-[(2-chlorophenyl)imino]-5-(4-hydroxy-3-nitrobenzylidene)-1,3-thiazolidin-4-one, PHOSPHATE ION, Serine/threonine-protein kinase pim-1 Authors: Parker, L.J, Handa, N, Yokoyama, S. Deposit date: 2012-04-13 Release date: 2012-08-08 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Flexibility of the P-loop of Pim-1 kinase: observation of a novel conformation induced by interaction with an inhibitor Acta Crystallogr.,Sect.F, 68, 2012
与抑制剂(2E,5Z)-2-(2-氯苯亚氨基)-5-(4-羟基-3-硝基苯亚甲基)噻唑烷-4-酮结合的Pim-1激酶晶体结构
描述符：(2Z,5Z)-2-[(2-氯苯基)亚氨基]-5-(4-羟基-3-硝基苯亚甲基)-1,3-噻唑烷-4-酮、磷酸根离子、丝氨酸/苏氨酸蛋白激酶（Serine/threonine-protein kinase）Pim-1
作者：Parker, L.J、Handa, N、Yokoyama, S.
存储日期：2012-04-13
发布日期：2012-08-08
最后修改日期：2023-11-08
实验方法：X射线衍射（分辨率2.8 Å）
引用文献：Pim-1激酶P环的柔性：与抑制剂相互作用诱导的新型构象的观测，发表于Acta Crystallogr.,Sect.F, 68, 2012
创建时间：
2012-04-13
