Cardiac hypertrophic response

Integrated schematic of the more extensively characterized intracellular signal-transduction pathways that coordinate the cardiac hypertrophic response. During development and in response to physiological stimuli or pathological insults, the heart undergoes hypertrophic enlargement, which is characterized by an increase in the size of individual cardiac myocytes.整合了详细描述的细胞内信号转导通路图示，这些通路协调了心脏肥大反应。在发育过程中以及对生理刺激或病理损伤的应答中，心脏经历肥大性增大，其特征为单个心肌细胞的体积增加。