Copper-Mediated Direct Aryloxylation of Benzamides Assisted by an N,O‑Bidentate Directing Group
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Copper-mediated selective mono- or diaryloxylation of benzamides has been achieved by using 2-aminopyridine 1-oxide as a new and removable N,O-bidentate directing group. The reaction system shows a broad substrate scope and provides a straightforward way for the synthesis of mono- and diaryloxylated benzoic acids.
创建时间:
2016-02-18



