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eccDNA Atlas

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国家生物信息中心2025-10-11 更新2025-03-15 收录
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http://lcbb.swjtu.edu.cn/eccDNAatlas/index.html
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资源简介:
Extrachromosomal circular DNAs (eccDNAs) represent a large category of nonmitochondrial and nonplasmid circular extrachromosomal DNA, and eccDNAs play an indispensable role involved in various aspects such as tumorigenesis, immune responses and biomarker, etc. Here, we developed eccDNA Atlas, a user-friendly database of eccDNAs that aims to provide a high-quality and integrated resource for browsing, searching and analyzing eccDNAs such as sequence, function/characteristic, validation strategies, etc. from multiple species. eccDNA Atlas currently containing 629,987 eccDNAs and 8,221 ecDNAs manually curated from literatures and 1,105 ecDNAs predicted by AmpliconArchitect based on WGS data involved in 66 diseases, 57 tissues and 319 cell lines. Furthermore, abundant annotations and analyzing utilities were provided to explore eccDNA Atlas eccDNAs or user-defined eccDNAs such as oncogenes, typical enhancers, super enhancers, gene expression, survival, genome visualization, etc.
提供机构:
Southwest Jiaotong University
创建时间:
2023-02-07
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