Expression data from the uterus of ovariectomized young adult rats treated for three days with E2, 3-MC, E2+3-MC

Examination of crosstalk between Aryl hydrocarbonreceptor (AHR) and Estrogen receptor (ER) in the rat uterus on the level of mRNA transcriptome The study was designed to see the overall gene-expression change in the uterus induced by E2, the AHR ligand 3-MC alone and in combination with E2. Ovariectomized young adult rats were treated with vehicle control (DMSO), 4µg/kg/d 17β-Estradiol (E2), 15 mg/kg/d 3-Methylcholanthrene (3-MC) and E2 + 3-MC for three consecutive days. Uteri were obtained 24 h after the last treatment. Biological samples from three rats were analyzed for each treatment group.