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Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells

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NIAID Data Ecosystem2026-03-12 收录
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To inhibit INS expression, we used shRNA to target the INS promoter. We find that knocking down INS expression with such an shRNA targeting the INS promoter significantly affects expression of 259 genes. mRNA profiles of EndoC βH1 with or without shRNA targetting INS promoter were generated by deep sequencing, in triplicate, using Illumina Hiseq 2500.

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2021-07-27
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