Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore).

Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore). Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... Authors: Nguyen, P.Q, Huecas, S, Plaza-Pegueroles, A, Fernandez-Tornero, C. Deposit date: 2022-03-01 Release date: 2023-04-05 Last modified: 2025-07-09 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration. Nat Commun, 14, 2023

分辨率为2.7埃的酿酒酵母RNA聚合酶III（RNA Polymerase III）-Ty1整合酶（Ty1 integrase）复合物结构（聚焦研究亚基C11，漏斗孔区域不含C11的C端锌带状基序）。相关亚基：DNA依赖的RNA聚合酶III亚基RPC1、DNA依赖的RNA聚合酶III亚基RPC10、DNA依赖的RNA聚合酶III亚基RPC2等。作者：Nguyen P.Q.、Huecas S.、Plaza-Pegueroles A.、Fernandez-Tornero C.。存档日期：2022-03-01；发布日期：2023-04-05；最后修改日期：2025-07-09。实验方法：电子显微镜（分辨率2.76埃）。引用文献：《靶向逆转录转座子整合中Ty1整合酶锚定RNA聚合酶III的结构基础》，《自然·通讯》（Nature Communications），第14卷，2023年。