Claidex Failure Atlas v1.1
收藏Zenodo2026-05-20 更新2026-05-26 收录
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https://zenodo.org/doi/10.5281/zenodo.20301169
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资源简介：
Claidex Atlas — v1.1
A curated, machine-readable corpus of documented drug-development failures (terminated programs, missed primary endpoints, regulatory holds, market withdrawals) sourced from ClinicalTrials.gov, FDA AdCom outcomes, EMA CHMP minutes, SEC 8-K filings, and peer-reviewed literature, with structured links to gene, target, disease, and trial identifiers.
Generated 2026-05-20 from the Claidex knowledge graph.
Snapshot statistics
Claims: 11
Distinct diseases: 11
Distinct targets: 11
Distinct sponsors: 10
Mechanisms (target × archetype): 4
Phase distribution
PHASE1: 1
PHASE1/PHASE2: 1
PHASE2: 4
PHASE3: 5
Failure archetype distribution
biomarker_failure: 1
efficacy_failure: 5
enrollment_collapse: 1
sponsor_decision: 4
Files
claidex-failure-atlas-v1.1.csv — every claim, frozen column order.
claidex-failure-atlas-v1.1.json — mechanism-level graph aggregates.
Licence: CC-BY-4.0. Homepage: http://localhost:3000.
Citation: Claidex Failure Atlas v1.1 (2026-05-20).
提供机构：
Zenodo创建时间：
2026-05-20
