Chronic inflammation permanently reshapes tissue-resident immunity in celiac disease. Chronic inflammation permanently reshapes tissue-resident immunity in celiac disease

Chronic inflammation driven by persistent antigenic challenge with dietary gluten permanently reshapes the tissue-resident TCRgd+ intraepithelial lymphocyte compartment in patients with celiac disease. Overall design: Transcriptional profiles of ex vivo sorted Vd1+ IELs from Control, Active CeD, and GFD CeD patients