Response to lupus antibodies of a human cardiac tissue model composed of cardiomyocytes and myofibroblasts. Response to lupus antibodies of a human cardiac tissue model composed of cardiomyocytes and myofibroblasts

RNASeq study of how a human cardiac tissue model composed of cardiomyocytes and myofibroblast responds to lupus antibodies Overall design: a. Tissue model treated with antibodies from healthy subjects (n=3). b. Tissue model treated with antibodies from subjects with lupus but not myocarditis (n=3) c. Tissue model treated with antibodies from subjects with lupus and myocarditis but with a preserved left ventricular ejection fraction (n=4) d. Tissue model treated with antibodies from subjects with lupus and myocarditis but with a reduced left ventricular ejection fraction (n=4)