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Selection of HIV-1 for Resistance to Fifth Generation Protease Inhibitors Reveals Two Independent Pathways to High-Level Resistance

NIAID Data Ecosystem2026-03-13 收录

HIV耐药性

蛋白酶抑制剂耐药机制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA853351 数据链接链接失效反馈

官方服务：

资源简介：

Using Primer ID MiSeq to study different pathways for HIV-1 protease drug resistance mutations.

应用场景：

创建时间：

2022-06-27

HIV耐药性

病毒基因变异

Frequency of occurrence of mutations and/or polymorphisms in protease by HIV subtypes.

NIAID Data Ecosystem50

Table S1 - A Very Low Geno2pheno False Positive Rate Is Associated with Poor Viro-Immunological Response in Drug-Naïve Patients Starting a First-Line HAART

HIV-1治疗应答

HIV耐药性

Factors related to immunological and virological response in HIV-1 infected patients starting their first-line HAART (Cox Models). (DOC)

NIAID Data Ecosystem50

Patient characteristics in the Hospital Database (n = 120).

HIV耐药性

抗逆转录病毒治疗

*defined as high-level resistance to at least one agent from the class. **defined as follows: First-line: no known history of resistance to any agent, and maximum change of 1 class of drugs. Second-li

NIAID Data Ecosystem30

ATN 061 PT/PI Codon Mutation Identification Dataset in Preservation and Expansion of T-cell Subsets Following HAART De-intensification to Atazanavir/ritonavir (ATV/r) in Adolescents and Young Adults with CD4 + T Cells > 350 cells/mm3 Initiating HAART

HIV抗病毒治疗

HIV耐药性

Data from Genotypic Resistance Results Form [CRF 3, codon mutation identification table (PT/PI)] Study Description A randomized, proof-of-concept study of adolescents and young adults aged 18-24 years

NIAID Data Ecosystem50

Correlation between the phenotypic drug susceptibility and low frequency variants in Taiwanese CRF07_BC early epidemic isolates.

HIV耐药性

低频变异与表型关联

Correlation between the phenotypic drug susceptibility and low frequency variants in Taiwanese CRF07_BC early epidemic isolates.

NIAID Data Ecosystem40