The Keap1-Nrf2-Bach1 signaling mediates UBR7 negative regulation of HK2 to inhibit glycolysis and HCC tumorigenesis [RNA-seq]. The Keap1-Nrf2-Bach1 signaling mediates UBR7 negative regulation of HK2 to inhibit glycolysis and HCC tumorigenesis [RNA-seq]
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA725845
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We found that Keap1-Nrf2 signaling pathway mediates UBR7 to regulate HK2 expression through the modification of histone H2BK120 monoubiquitination, thereby inhibiting glycolysis and HCC tumorigenesis. Overall design: The gene expression of in wild-type and Alb-Cre;UBR7fl/fl mouse liver primary cells were detected were detected by RNA sequencing.
创建时间：
2021-04-28
