Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE2865

Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE2865 Descriptor: 1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid, Glycogen phosphorylase, liver form, ... Authors: Wendt, K.U, Dreyer, M.K, Anderka, O, Klabunde, T, Loenze, P, Defossa, E, Schmoll, D. Deposit date: 2008-02-29 Release date: 2008-05-27 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry, 47, 2008处于紧张态的人类糖原磷酸化酶（glycogen phosphorylase）与变构抑制剂AVE2865形成的复合物 配体描述：1-{2-[3-(2-氯-4,5-二氟苯甲酰基)脲基]-4-氟苯基}哌啶-4-羧酸；肝型糖原磷酸化酶…… 作者：Wendt, K.U.、Dreyer, M.K.、Anderka, O.、Klabunde, T.、Loenze, P.、Defossa, E.、Schmoll, D. 入库日期：2008-02-29 发布日期：2008-05-27 最后修改日期：2025-03-26 实验方法：X射线衍射（3.3 Å） 引用文献：变构糖原磷酸化酶抑制剂的热力学表征。《生物化学》，47卷，2008年