This library holds all H2MM input and analysis files for the H2MM analysis of Free promoter, This was performed to identify the values of BIC' at a 2-state model, expected for free DNA with a single c
An NMR-based relative binding affinity measurement method has been developed in which differences in the binding affinities of different hosts toward a particular guest (ΔlogKass values) are measured
The excel file contains modeled distributions of Kd values for progressive rounds of aptamer selection and proposed bulk affinity workflow. The origin file includes the construction of gaussi
The core jupyter notebooks demonstrating mpH2MM using real nsALEX data on DNA hairpin and theRNAP complex with the RPo transcription bubble. Also included are the jupyter notebooks for generating simu
In single molecule fluorescence studies, background emission from labeled substrates often restricts their concentrations to non-physiological nanomolar values. One approach to address this challenge
