This library holds all H2MM input and analysis files for the H2MM analysis of Free promoter, This was performed to identify the values of BIC' at a 2-state model, expected for free DNA with a single c
The core jupyter notebooks demonstrating mpH2MM using real nsALEX data on DNA hairpin and theRNAP complex with the RPo transcription bubble. Also included are the jupyter notebooks for generating simu
Michaelis-Menten binding curves to evaluate Kd (nM) were performed as described in Materials and Methods; standard deviation values were determined from three independent experiments.
This library holds all H2MM input and analysis files for the H2MM analysis of Free promoter, This was performed to identify the values of BIC' at a 2-state model, expected for free DNA with a singl
An NMR-based relative binding affinity measurement method has been developed in which differences in the binding affinities of different hosts toward a particular guest (ΔlogKass values) are measured