FAIRsharing record for: G4Atlas: a comprehensive transcriptome-wide G-quadruplex database

This FAIRsharing record describes: G4Atlas is a transcriptome-wide G-quadruplex database containing and visualising transcriptome RNA G-quadruplex (rG4) experimental data, generated from rG4-seq, chemical profiling and ligand-binding methods. rG4 is a vital RNA tertiary structure motif that involves the base pairs on both Hoogsteen and Watson-Crick faces of guanines, and is relevant to the post-transcriptional regulation of gene expression. RNA secondary structure prediction information across both experimentally identified and unidentified rG4s is also included to enable users to display any potential competitive folding between rG4 and RNA secondary structures. As such, G4Atlas allows users to explore the general functions of rG4s in diverse biological processes, and provides a starting point for further data-driven deep learning algorithms to examine rG4 structural features.