Mutation frequencies analyzed for different functional regions of mtDNA in mothers and pups.

The D-loop and noncoding region are listed separately to allow for better comparison to reported results on the D-loop region solely. The D-loop region in mouse mtDNA has a size of 877 bp compared with 934 bp considering all noncoding regions. p-Values were corrected for multiple testing (separately for mother versus pup comparisons and D-loop versus non–D-loop comparisons) using the method of Benjamini–Hochberg to control the false discovery rate. mtDNA, mitochondrial DNA. (XLSX)