Structure of human PD-L1 in complex with clinically evaluated inhibitor

Structure of human PD-L1 in complex with clinically evaluated inhibitor Descriptor: (5~{S})-5-[[[5-[2-chloranyl-3-[2-chloranyl-3-[6-methoxy-5-[[[(2~{S})-5-oxidanylidenepyrrolidin-2-yl]methylamino]methyl]pyrazin-2-yl]phenyl]phenyl]-3-methoxy-pyrazin-2-yl]methylamino]methyl]pyrrolidin-2-one, GLYCEROL, Programmed cell death 1 ligand 1 Authors: Golebiowska-Mendroch, K, Slota, A, Plewka, J, Magiera-Mularz, K. Deposit date: 2025-01-15 Release date: 2025-06-18 Last modified: 2025-07-30 Method: X-RAY DIFFRACTION (1.46 Å) Cite: Characterization of Clinically Evaluated Small-Molecule Inhibitors of PD-L1 for Immunotherapy. Acs Med.Chem.Lett., 16, 2025