Pro-fibrotic and pro-inflammatory genes driven by steroid hormone imbalance in the prostate. Pro-fibrotic and pro-inflammatory genes driven by steroid hormone imbalance in the prostate

The study involved analysis of the effect of testosterone and estradiol hormone pellet implantation with the mouse fibrosis Nanostring panel Overall design: Mice were implanted with 25 mg testosterone and 2.5 mg estradiol slow-release pellets or underwent sham surgery. Prostates were collected two weeks later.