Examples of polar ratio in protein complexes.

Polar ratio is the number of polar contacts divided by the total [polar + apolar] number of contacts. These protein complexes are for proteins that bind to both protein partners (ratio p-p, left) and synthetic small molecules (ratio p-sm, right). The PDB code includes the interacting chains, for example 1TNF(AB:C) denotes chain A and B interacting with chain C of the TNF trimer, whereas 2AZ5 (C&D) denotes chains C and D interacting with the small molecule. When available, affinity measure and units is specified in table.