Summary of published motility models.

Model components and computational methods of articles surveyed in this review. In columns 2–6 an “x” indicates inclusion (to some extent) of a given layer of biological complexity. Column heading abbreviations are as follows: CD, cytoskeleton dynamics; CF, cytosolic flow; SD, signaling dynamics; MM, membrane mechanics; AD, adhesion dynamics. The boundary treatment column (column heading Boundary) indicates the method used to handle the moving boundary of the cell: LMP, LSM, PFM, or the CPM. The PDE Methods column (column heading PDEM) indicates the procedure used to discretize model PDEs: Finite Difference Method (FDM), Finite Volume Method (FVM), or Finite Element Method (FEM).