MALT1 in complex with compound 1

MALT1 in complex with compound 1 Descriptor: Mucosa-associated lymphoid tissue lymphoma translocation protein 1, ~{N}1-(3-chloranyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-~{N}4-[2-(trifluoromethyl)pyrimidin-4-yl]cyclohexane-1,4-diamine Authors: Kack, H, Oster, L. Deposit date: 2021-07-30 Release date: 2021-11-17 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Discovery and optimization of cyclohexane-1,4-diamines as allosteric MALT1 inhibitors. Eur.J.Med.Chem., 227, 2021与化合物1结合的MALT1复合物描述：黏膜相关淋巴组织淋巴瘤易位蛋白1（Mucosa-associated lymphoid tissue lymphoma translocation protein 1）与~N1-(3-氯-[1,2,4]三唑并[4,3-b]哒嗪-6-基)-~N4-[2-(三氟甲基)嘧啶-4-基]环己烷-1,4-二胺；作者：Kack, H.、Oster, L.；提交日期：2021-07-30；发布日期：2021-11-17；最后修改日期：2024-01-31；实验方法：X射线衍射（分辨率2.19 Å）；引用文献：《环己烷-1,4-二胺类变构MALT1抑制剂的发现与优化》，《欧洲药物化学杂志》（Eur.J.Med.Chem.），227卷，2021年