Profiles of Epigenetic Histone Post-translational Modifications at Type 1 Diabetes Susceptible Genes
收藏NIAID Data Ecosystem2026-03-07 收录
官方服务:
资源简介:
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
应用场景:
创建时间:
2012-06-01
相关数据集
Distinct features in establishing H3K4me3 and H3K27me3 in pre-implantation embryos
Histone modifications play critical roles in regulating developmental genes expression during embryo development in mammals1,2. However, genome-wide analysis of histone modifications in pre-implantati
NIAID Data Ecosystem100
Long-Term Pancreatic Beta Cell Exposure to High Levels of Glucose but Not Palmitate Induces DNA Methylation within the Insulin Gene Promoter and Represses Transcriptional Activity
Recent studies have implicated epigenetics in the pathophysiology of diabetes. Furthermore, DNA methylation, which irreversibly deactivates gene transcription, of the insulin promoter, particularly th
Figshare2016-01-15 更新70
Environmental Factors Influence the Epigenetic Signature of Newborns from Mothers with Gestational Diabetes. Environmental Factors Influence the Epigenetic Signature of Newborns from Mothers with Gestational Diabetes
Here we investigated the degree by which epigenetic signatures in children from mothers with obesity or gestational diabetes mellitus are influenced by environmental factors. We profiled the DNA methy
NIAID Data Ecosystem50
Epigenetic changes in Langerhans islets preceding the onset of diabetes. Epigenetic changes in Langerhans islets preceding the onset of diabetes
Diabetes-resistant and diabetes-prone female New Zealand Obese mice were classified based on liver fat content and early blood glucose concentrations at 10 weeks of age before the onset of T2D. By usi
NIAID Data Ecosystem80
Genome-wide histone modification profiling using ChIP-seq of diabetic or non-diabetic murine bone marrow derived macrophages (BMDM) and haematopoietic stem cells (HSC)
Genome-wide histone modification profiling using ChIP-seq of diabetic or non-diabetic murine bone marrow derived macrophages (BMDM) and haematopoietic stem cells (HSC). Chromatin fragments were select
NIAID Data Ecosystem70



