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RNA-Seq of MC38 tumors in responder and non-responder CCF1 lines

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NIAID Data Ecosystem2026-05-02 收录
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In this study we investigated variation in responsiveness to anti-PD-1 using a model where we implanted the MC38 colorectal cancer cell line in genetically diverse host mice. To quantify differences in gene expression between tumors from responder and non-responder lines,we profiled four tumors from each of three responder lines and three non-responder lines. Of the four tumors from each line, two were treated with anti-PD-1 and two were treated with isotype control antibody.

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2024-08-12
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