Figure 2
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Figure 2: Nociceptive sensory afferent nerves innervate the developing kidney. (A) Wholemount immunostain of an E16.5 Trpv1Cre/+;R26tdTomato/+ kidney showing tdTomato+ (magenta) axons colocalizing with the pan-neuronal marker TUBB3 (green). A magnified inset from the merged shows tdTomato+ axons overlapping with TUBB3. (B) Trpv1Cre/+;R26tdTomato/+ P1 kidney section showing tdTomato signal (magenta) closely associating (arrowheads) with proximal tubules (LRP2, green) and tubule epithelium (ECAD, yellow). Tubules show non-specific tdTomato signal. (C) Trpv1Cre/+;R26tdTomato/+ P1 kidney section showing tdTomato signal (magenta) closely associating (arrowheads) with glomeruli (podocin, green) and endothelium (CD31, yellow). Tubules show non-specific tdTomato signal.
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UNC Dataverse
创建时间：
2024-07-18
