Additional file 3: Table S1. of Identification and annotation of conserved promoters and macrophage-expressed genes in the pig genome

GO enrichment analysis for the human genes with FANTOM5 human TSS unmapped to the pig genome. Table shows the list of GO terms enriched for two sets of human genes: (i) for which at least one FANTOM5 human TSS was not mapped to the pig genome (class referred to as genes_tss) and (ii) for which all the associated FANTOM5 human TSS were not mapped to the pig genome (class referred to as genes_none). GO enrichment analysis was performed against a background set consisting of all the human genes with a known associated FANTOM5 human TSS using GOrilla [54]. The columns from left to right indicate: GO terms ID; description of the GO term; P-value; FDR adjusted q-value (i.e. P-value corrected for multiple testing using the Benjamini and Hochberg’s method); Enrichment; total number of genes (N); total number of genes associated with a specific GO term (B); number of genes in the target set (n); number of genes in the intersection (b). Enrichment is defined as (b/n)/(B/N) [54]. The last column (Genes) displays the list of associated genes that appear in the optimal top of the list – each gene name is shown with its gene symbol followed by a short description of the gene. (XLS 1049 kb)