Switching of OAS1 splicing isoforms mitigates SARS-CoV-2 infection
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE174398
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资源简介：
We aimed to study impact of CDC-like kinase (CLK) inhibitor CaNDY on OAS1 splicing manipulation. Our data indicates CaNDY treatment induces switching of OAS1 splice isoforms to provide an increased resistance to SARS-CoV-2 infection. PolyA-tailed RNA profiles were obtained for Calu-3 cells, treated with 10 µM CaNDY (n=3) or 0.1% DMSO (n=3).
创建时间：
2025-03-12
