Case-control study for the association between TLR single nucleotide polymorphisms and end-stage renal disease per underlying disease category.

1Per allele odds ratios (OR) and 95% confidence intervals (CI) based on additive genetic logistic regression models adjusted for age and gender, taking case-control relatedness into consideration (DFAM algorithm). HGVS = Human Genome Variation Society.
2P-values are Bonferroni corrected.
3Post hoc estimates of the type II errors (100%–power) were calculated according to the methods by Skol et al. [23] with the data as mentioned in the table and an end-stage renal disease prevalence of 0.1% (estimate in The Netherlands).
Case-control study for the association between TLR single nucleotide polymorphisms and end-stage renal disease per underlying disease category.