Biological activities of crude extract, fraction, and compounds isolated from Cochliobolus sp. (UFMGCB-555) tested at a single dose of 20 ��g mL?1.

aPercentage of death of amastigote-like forms of Leishmania (Leishmania) amazonensis. Control drug: amphotericin B at 0.2 ��g mL?1.bPercentage inhibition of the enzyme trypanothione reductase. Clomipramine at 6 ��M was used as 50% inhibition control.cCytocidal activity (percentage of death of human cancer cells relative to the initial inoculum). Control drugs: etoposide at 16 ��g mL?1 and colchicine at 8 ��g mL?1.dnot tested.The values represent the mean��S.D. of at least 2 independent experiments.The minus symbol (?) means inactive.