Oncogenic MTOR signaling axis compensates BTK inhibition in a Chronic Lymphocytic Leukemia patient
收藏NIAID Data Ecosystem2026-05-01 收录
官方服务:
资源简介:
Mutation and transcriptome analysis and of an ibrutinib resistant patient.
应用场景:
创建时间:
2024-04-23
相关数据集
Additional file 2: Supplementary tables. of Epigenetic and genetic alterations and their influence on gene regulation in chronic lymphocytic leukemia
Table S1. Overlap and enrichment of repeated elements along dREs. Table S2. Enrichment of dREs in the regulatory domains of CLL-up/down-regulated genes. Table S3. Enrichment of gene groups to Gene Ont
DataCite Commons2024-12-16 更新100
Analysis of DNA methylation in normal B cells and chronic lymphocytic leukemia
Charting differences between tumors and normal tissue is a mainstay of cancer research. However, clonal tumor expansion from complex normal tissue architectures potentially obscures cancer-specific ev
NIAID Data Ecosystem90
Clinical and biological implications of target occupancy in chronic lymphocytic leukemia treated with acalabrutinib
Inhibition of the B-cell receptor pathway, and specifically of Bruton tyrosine kinase (BTK), is a leading therapeutic strategy in chronic lymphocytic leukemia (CLL). Target occupancy has been measured
NIAID Data Ecosystem30
RNA sequencing data from the CLL cell line HG3 (HG-3) by Oxford Nanopore Technologies based direct RNA long-read sequencing.
This is the sequencing data from direct RNA long-read sequencing by Oxford Nanopore Technologies of the chronic lymphocytic leukemia cell line HG3 (HG-3).Total RNA was extracted using the RNAeasy kit
DataCite Commons2025-01-15 更新100
Characterization of CD200 Ectodomain Shedding
We have previously reported the existence of a soluble form of CD200 (sCD200) in human plasma, and found sCD200 to be elevated in the plasma of Chronic Lymphocytic Leukemia (CLL) patients. CLL cells r
NIAID Data Ecosystem70



