Genome wide association study (GWAS) summary statistics, chronic pain broad and narrow in Mount Sinai BioMe
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Summary statistics for GWAS performed as part of 'A computational genetic- and transcriptomics-based study nominates drug repurposing candidates for the treatment of chronic pain' Cote et al (preprint DOI https://doi.org/10.1101/2025.03.07.25323591) readme: Genome wide association study summary statistics for analyses performed by Cote et al (associated with preprint DOI https://doi.org/10.1101/2025.03.07.25323591) in Mount Sinai BioMe cohort using PLINK Phenotypes: chronic pain (narrow), chronic pain (broad) Filenames biome_eur_broadchronicpain_gwas.broad.glm.logistic.hybrid.gzbiome_eur_narrowchronicpain_gwas.narrow.glm.logistic.hybrid.gz Column names and descriptions#CHROM Chromosome POSBase pair position IDVariant ID (CHR:POS:REF:ALT format) REFReference allele ALTAlternative allele PROVISIONAL_REF?Whether reference allele is marked as provisional (see PLINK documentation for more detail) A1Effect allele OMITTEDWhether variant omitted from GWAS regression model A1_FREQA1 allele frequency FIRTH?Whether penalized regression model used TESTType of test / underlying model OBS_CTCount of non-missing observations for variant OROdds ratio (effect size) LOG(OR)_SEStandard error of log(OR) Z_STATZ statistic PP value ERRCODEErrors, if any



