Additional file 2 of Sex specific molecular networks and key drivers of Alzheimer’s disease
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Additional file 2: Supplemental Table 2. Differential expression analysis of the comparisons of various groups as the combinations of sex, disease status, and APOE genotype. Multiple tests were adjusted using the Benjamini–Hochberg’sFDR method. Genes with an FDR adjusted p value less than 0.05 and fold changegreater than 1.2 were considered significant. A) Summary of the numbers of DEGsfrom different comparisons in different brain regionsreported in 2B and 2C. B) The DEGs in the PHG of the MSBB cohort from the comparisons of sex specific and APOE genotype specific AD versus control subjects as well as disease status and APOE genotype specific males versus females. C) The DEGs in the PFC from the ROSMAP cohort from the comparisons of sex and APOE genotype specific AD versus control subjects as well as disease status and APOE genotype specific males versus females.
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figshare
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2024-08-13



