Carbapenem-resistant Acinetobacter baumannii (CRAB) tested for susceptibility to meropenem/QPX7728

QPX7728 is a recently discovered ultra-broad-spectrum beta-lactamase inhibitor (BLI) with potent inhibition of key serine and metallo beta-lactamases. QPX7728 enhances the potency of many beta-lactams, including carbapenems, in gram-negative bacteria producing various beta-lactamases. The potency of meropenem alone and in combination with QPX7728 (1-16 ug/ml) was tested against 375 clinical isolates of carbapenem-resistant Acinetobacter baumannii (CRAB) including 177 isolates with sequenced genomes. Sequence results for these 177 genomes are deposited here.