We present evidence of mechanistically diverse allosteric relays converging on a few peptidyltransferase center (PTC) nucleotides, and propose a general model of antibiotic resistance mediated by thes

NIAID Data Ecosystem10

MD Simulation of DNA topoisomerase IV subunit C (parC) protein of P. aeruginosa, with mutations recorded in 1999 in complex with Levofloxacin (LEV) ligand molecule

分子相互作用模拟

细菌耐药性机制

Mutated sequences of DNA topoisomerase IV (subunit C) protein (mutations recorded in 1999) associated with P. aeruginosa are modeled and docked with a molecule of Levofloxacin. The data from subsequen

Zenodo2026-06-08 更新00

ReGAIN Supplemental Figures

细菌耐药性机制

基因共现网络分析

The rampant rise of multidrug-resistant (MDR) bacterial pathogens poses a serious health threat, necessitating innovative tools to unravel the complex genetic underpinnings of antimicrobial resistance

Figshare2025-05-08 更新10

Table_2_Characterization and Identification of a novel chromosome-encoded metallo-β-lactamase WUS-1 in Myroides albus P34.DOCX

新型β-内酰胺酶鉴定

细菌耐药性机制

In this study, we identified and characterized a novel chromosomally-encoded class B metallo-β-lactamase (MBL) gene designated blaWUS-1 in a carbapenem-resistant isolate Myroides albus P34 isolated fr

NIAID Data Ecosystem10

Escherichia coli Raw sequence reads. Escherichia coli

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