Structural Biology BAG - Portugal

The Portuguese MX BAG includes 16 PIs from three different institutions. Our research interests include soluble and membrane proteins of biomedical interest from humans or pathogenic organisms, several of which can be drug targets. A focal point of the Portuguese MX BAG is also structural enzymology, aimed at the elucidation of reaction mechanisms, characterization of active sites, and understanding inhibition tolerance in proteins with potential biomedical or biotechnological applications. In several cases, complementary Structural Biology approaches are employed, combining MX with SAXS and CryoEM.