Hand and Arm Dysfunction is Prevalent Following Hemodialysis Access Placement and Associated with Higher Rate of Access Failure

This project aimed to map transcriptome changes in the forearm skeletal muscle of patients with chronic kidney disease undergoing hemodialysis access placement surgery. Muscle biopsies were obtained from the brachioradialis muscle pre- and at several timepoints post-operatively. Overall design: bulk RNA sequencing was performed on brachioradialis muscle specimens obtained from CKD patients undergoing hemodialysis access placement surgery