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Regioselective Iodoazidation of Alkynes: Synthesis of α,α-Diazidoketones

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NIAID Data Ecosystem2026-03-08 收录
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Aryl alkyl alkynes reacted with N-iodosuccinimide (NIS) and trimethylsilyl azide (TMSN3), leading to α,α-diazidoketones via the regioselective addition of IN3 to alkynes. Huisgen cyclization of α,α-diazidoketones generated bis-triazole compounds.

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2016-02-14
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