Rh<sub>2</sub>(<i>R</i>‑TPCP)<sub>4</sub>‑Catalyzed Enantioselective [3+2]-Cycloaddition between Nitrones and Vinyldiazoacetates
收藏NIAID Data Ecosystem2026-03-07 收录
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资源简介：
Rhodium-catalyzed reaction of vinyldiazoacetates with nitrones results in a formal [3+2]-cycloaddition to generate 2,5-dihydroisoxazoles with high levels of asymmetric induction. The cascade reaction begins with a vinylogous addition event, followed by an iminium addition ring-closure/hydride migration/alkene isomerization cascade. Dirhodium tetrakis(triarylcyclopropanecarboxylates) are the optimum catalysts for this process.
创建时间：
2013-10-02
