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Identification of intrinsically immunogenic small cell lung carcinoma (SCLC) subpopulations [Cell line]

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP309372
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资源简介:
SCLC is molecularly and immunologically heterogenous. Here, using transcriptional and epigenomic profiling of plastic SCLC states in human and mouse cell lines, and patient samples, we define the phenotype of a SCLC population marked by increased MHC Class I antigen presentation. Overall design: Examination of paired transcriptome and H3K27Me3 in isogenic SCLC cell lines, and transcriptomes of MHC Class I high vs. low SCLC cell lines and patient samples
创建时间:
2021-03-07
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