JAK2 inhibition in Philadelphia chromosome like acute lymphoblastic leukemia
收藏NIAID Data Ecosystem2026-03-11 收录
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资源简介：
CRLF2 rearranged Ph-like ALL cells are driven by oncogenic cytokine receptor signaling mediated by CRLF2 and JAK2. MHH-cALL4 cells were treated with ruxolotinib (JAK2 inhibitor) to provide insight into mechanisms of drug resistance. MHH-cALL4 cells were cultured in vitro in RPMI 20%FBS 1%Pen/Strep and treated either with DMSO or 1uM ruxolitinib for 12h.
创建时间：
2020-06-01
