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Progressive ratio in protein-restricted vs. non-restricted rats

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NIAID Data Ecosystem2026-03-13 收录
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https://zenodo.org/record/5409200
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These data are from experiments studying motivation in protein-restricted rats using progressive ratio responding for food pellets conducted at University of Leicester, UK. These findings will be published in Chiacchierini et al. (2022) bioRxiv. Detailed methods for the experiment can be found in this paper. Full citation to a peer-reviewed publication is expected to follow. Briefly, data are from operant behavior sessions (FR1, FR3, etc) recorded on Med Associates hardware. Accompanying analysis code as a Jupyter notebook is available on Github (https://github.com/mccutcheonlab/PRPR).  The data are provided as a compressed zip file containing the following: Folder with raw datafiles from experiment using nutritionally-balanced grain pellets (PRPR_exp1) Folder with raw datafiles from experiment using protein (35% casein) pellets (PRPR_exp2) Excel file with metadata to accompany each raw datafile (PRPR_metafiles.xls) The raw datafiles are Med Associates files in the stripped format. Timestamps of individual lever presses and reward deliveries are included in the raw datafiles and can be extracted but are not used here. PRPR_metafiles.xls contains sheets (metafile_exp1 and metafile_exp2) with the following information for each datafile: filename rat ID session number box diet group (NR, non-restricted or PR, protein-restricted) date ratio (FR, fixed ratio or PR, progressive ratio) pellet type (grain or protein) responses rewards breakpoint PRPR_metafiles.xls also contains sheets (freeaccess_exp1 and freeaccess_exp2) with data from the free access tests showing grams of food consumed on two consecutive days for each rat in the study.
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2022-02-10
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