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The goal of these studies was to demonstrate how dermal TRMs maintain the population size and M2-like characteristics during classical TH1 immune response against L. major infection.
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创建时间：
2019-09-13
相关数据集
Gene expression profile of Leishmania major infected THP1 cell lines
Nanostring nCounter gene expression analysis on L. major infected wild type versus knockout THP1 cells was performed based on 784 genes with nCounter PanCancer Immune Profiling CS Kit (no MK). In the
NIAID Data Ecosystem50
In vivo single-cell and bulk transcriptomics reveals murine Leishmania major infection drives a pro-inflammatory signature alongside a signature of decreased ribosomal biogenesis.
Leishmania parasites cause cutaneous leishmanina (CL), a pathologic disease characterized by disfiguring, ulcerative skin lesions. Both parasite and host gene expression following infection with vario
NIAID Data Ecosystem10
Absolute number (×10 4 ) of IL-12 and IL-6 producing dermal CD11c + DCs and F4/80 + macrophages in C57BL/6 and BALB/c mice at 48 h post infection with L . major alone or in combination with 50 μg Pam3CSK4.
Data represent mean ± SD. n = 3 mice. Significant differences were determined by Student t test. P values obtained from comparing both groups are included in the table. Absolute number (×104) of IL-12
NIAID Data Ecosystem10
Table_3_Melatonin and Leishmania amazonensis Infection Altered miR-294, miR-30e, and miR-302d Impacting on Tnf, Mcp-1, and Nos2 Expression.XLS
Leishmaniases are neglected diseases that cause a large spectrum of clinical manifestations, from cutaneous to visceral lesions. The initial steps of the inflammatory response involve the phagocytosis
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Data_Sheet_4_Infection of Human Neutrophils With Leishmania infantum or Leishmania major Strains Triggers Activation and Differential Cytokines Release.PDF
Leishmaniases are neglected diseases, caused by intracellular protozoan parasites of the Leishmania (L.) genus. Although the principal host cells of the parasites are macrophages, neutrophils are the
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