Non-coding and coding transcriptional profiles are significantly altered in pediatric Retinoblastoma tumors

To find out the transcriptomic signature of Retinoblastoma compared to adult Retina. The methadology used was RNA sequencing using Illumina Platform. Overall design: This is the first transcriptomic report on RB tumours from patients compared to retina. This experiment gives valuable information about gene expression fusions and Long Non-coding RNAs and RNA mutations