five

RNAseq analysis of two PWS mouse model brains

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https://www.ncbi.nlm.nih.gov/sra/SRP363231
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We report the RNAseq nalysis of transcription in the brains of two mouse models for PWS. PWScr and and PWS-IC mice have overlapping and and distinct changes in gene expression and isoform usage. The increased number of changes seen in PWS-IC brain are enriched for genetic variants associated with psychotic illness. Overall design: Examination of whole brain at P0 in PWScr mice and their wildtype littermates, and PWS-IC mice and their littermates
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2024-02-29
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